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The phase 2 and phase 3 clinical trials used the same starting dose for all weight groups

doi: 10.1007/s12035-018-1352-x 149 GombartAFPierreAMagginiS

To reconstitute any peptide, GLP-1, or supporting compound such as NAD+, divide the total peptide amount in the vial (mg) by the amount of bacteriostatic (BAC) water added (mL) to find the concentration (mg/mL), then divide the desired dose (mg) by this concentration (mg/mL) to determine the injection volume in syringe units

Marques C, Hadjab F, Porcello A, Loureno K, Scaletta C, Abdel-Sayed P, Hirt-Burri N, Applegate LA, Laurent A

Blend them until they are finely pureed