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As with any investigational substance, unknown or idiosyncratic responses cannot be excluded, and the long-term safety of BPC-157 has not been formally characterised

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Hakaru Hashimoto The first indication of an immunologic abnormality in this disease was an elevation of the plasma gamma globulin fraction detected by Fromm et al.(3) This finding, together with abnormalities in serum flocculation test results(4) indicated that the disease might be related to a long-continued autoimmune reaction

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Antibody formation Greater levels of anti-cagrilintide antibodies were detected with higher doses of cagrilintide in clinical trials