Drugs that target inflammation, synaptic dysfunction, insulin resistance, and oxidative stress, all of which lead to neuronal death and neurodegeneration, should also be considered for an effective therapeutic strategy for AD and PD
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Acknowledgements This work has been supported by the Amsterdam Reproduction & Development Research Institute and the China Scholarship Counsel (grant number 202006300005 to Wenqing Liu)
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These studies must involve well-characterized patient sub-sets to better delineate genotype-phenotype relationships
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