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Until recently, ergothioneine was an obscure amino acid derivative hiding in plain sight in everyday foods

J Biol Chem 213:6168 Nakamichi N, Nakayama K, Ishimoto T et al (2016) Food-derived hydrophilic antioxidant ergothioneine is distributed to the brain and exerts antidepressant effect in mice

However, it's crucial to note that one can have Hashimoto's without experiencing hypothyroidism, and vice versa

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