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Zepbound (tirzepatide) is an injectable prescription medicine approved for the treatment of obesity

Other urinary concerns with semaglutide UTIs are not the only urinary issue that semaglutide users report

In contrast, semaglutide works through a different mechanism that does not affect urinary glucose excretion

However, in phase 3a trials, mean baseline Patient Health Questionnaire-9 (PHQ-9) scores for liraglutide vs placebo improved at the treatment end

Wegovy injection showed weight loss of 15% in its key trial, versus 2% for placebo, while Zepbound showed 21% on its highest dose, compared with 3% for those on placebo