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Many pharmaceutical companies have tried to develop drugs that target Mcl-1, but this has been difficult because the interaction between Mcl-1 and its target protein occurs in a long stretch of 20 to 25 amino acids, which is difficult to block with the small molecules typically used as drugs

In preclinical studies, BPC-157 has shown a favorable safety profile

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even if peptide mechanisms prove effective in humans, reversal would likely require sustained treatment and would be limited to veins with repairable (not completely destroyed) architecture

Adding more water lowers the concentration, so you would draw a larger volume to reach the same dose