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It is therefore suggested that the pathophysiology of PKU is more complex than initially expected and that more recently discovered neurological processes, including alterations in protein synthesis and energy homeostasis, increased oxidative stress and hypomyelination, could thus complicate the establishment of a good genotype phenotype correlation [15, 16]

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GLP-1 receptor agonists are effective in reducing glucose, enhancing satiety, promoting weight loss, and lowering cardiovascular risks in high-risk patients

This indicates that NNMT could be a potential biomarker for cancer prognosis, and the inhibition of this enzyme through 5 Amino 1 MQ can act as an anti-cancer treatment