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Reduced potency means inadequate glycemic control

The 4.8 mg dose showed the greatest efficacy

For everyone else, the current evidence does not show a clear elevated risk in humans, but the monitoring guidelines exist for a reason

Another recent study, 344 which examined the impacts of another GLP-1, GIP and GCGR tri-agonist in rodents, found that treatment with this agonist decreased body weight, food intake and hyperglycaemia