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SP regulated oxidative stress and reprogrammed SMs to an anti-inflammatory M2-like phenotype, which restricted inflammation in an RA-specific context and restored synovial homeostasis

Analysis of VP5 phenotypes with Imaris software HeLa cells seeded on coverslips were transfected with 25 nM of siDDX3X (Dharmacon cat # D-006874-01-0002) or NC1 (IDT) for 48 h as described previously 25 and then mock-treated or infected with wild-type strain 17 + at an MOI of 5 for 9 h

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doi: 10.1210/jcem.83.12.5341 165 MutaguchiKYasumotoHMitaKMatsubaraAShiinaHIgawaMet al