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Specifically, the application of MSC-Ch-gel effectively addressed microorganisms associated wounding by minimizing inflammation, enhanced re-epithelialization, and stimulated well-vascularized granulation tissue due to the pleiotropic and multi-targeted effects of stem cell secretome thus decreasing the application of antibacterial and antiseptic drugs

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Red cell DAMPs and inflammation

Activated caspase-8 can either directly cleave and activate executioner caspases, or in many beta cells, cleave the BH3-only protein Bid to produce tBid, which is transported to the mitochondria and potentiates the intrinsic pathway, a kind of crosstalk [99]