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Similarly, stacking AHK-Cu with high-dose vitamin C (above 1000mg) creates a chemical interaction that can oxidize the copper complex before it reaches tissue targets

When you eat, GLP-1 signals your pancreas to release insulin, lowering blood sugar

doi:10.1001/archderm.1922.02360060046004\ Wikipedia contributors, Doctrine of signatures, Wikipedia, The Free Encyclopedia, (accessed August 28, 2024)

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But it has not been ruled out, and the FDA's briefing documents noted it as an uncharacterized risk requiring further investigation before any approval