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More recently, the use of IPI504 (Retaspimycin, a synthetic derivative of Geldanamycin), in an in vitro model of age-related macular degeneration (AMD) on senescent ARPE-19 (human arising retinal pigment epithelial cells), leads to a decrease of SA--Galactosidase positive cells, associated with a downregulation of senescence-associated gene expression as well as SASPs secretion, suggesting that in some cases HSP90 inhibitors could also be used as senomorphics 27

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See what research suggests in the What It Does section of our Acetyl-L-Carnitine Review

These evaluations help us understand the underlying factors affecting inflammation, tissue health, skin regeneration, metabolic balance, and overall recovery capacity before designing a personalised, medically supervised peptide therapy program

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