Overall, our results demonstrate that oxygen-to-sulfur (O-to-S) exchange provides a versatile electrophile tailoring strategy for late-stage optimizations, leading to the discovery of -chlorothioacetamides and -fluorothioacetamides as electrophilic warhead chemotypes
Retrieved 24 June 2024
Long-term data continues accumulating, and no significant new safety signals have emerged with broader use
Ranneh Y, Hamsho M, Fadel A, Ali Osman HM, Ali EW, Mohammed Kambal NH
Nutritional interventions can target key pathophysiological mechanisms of endometriosis, such as systemic inflammation, oxidative stress, and hormonal imbalance, offering potential symptom relief and improved clinical outcomes