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Elevated Bcl-2/Bax ratio and reduced cleaved caspase-3/PARP levels indicate anti-apoptotic mechanism

[DOI] [PMC free article] [PubMed] [Google Scholar] 373

Regulatory status: The FDA determined in 2022 that BPC-157 raises concerns that preclude its use in compounded preparations, placing it on the list of substances that may not be compounded under Sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act

Functionally, BPC-157 looks most like a multi-pathway angiogenic and growth-factor-receptor modulator with broad tissue specificity

This NO modulation affects blood flow, inflammation, and cellular signaling throughout healing tissues