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Current Diabetes Reviews , 13 (4), 428436

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Vanessa Zann, Vice President of Scientific Consulting, Translational Pharmaceutics- Clinical Pharmacology USA, and Katie Pepper, Senior Project Scientist, learn how PF614-Multi-Pill Abuse Resistance (MPAR) was designed to deliver desired opioid-level analgesia at therapeutic dose levels while providing overdose protection if consumed at higher-than-intended doses, through a unique trypsin-activated prodrug approach: To view or add a comment, sign in Can we observe a second peak plasma drug concentration (secondary Cmax) after intravenous (IV) drug administration