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Triggers include genetic susceptibility (HLA-DR3/DR4) and environmental factors (viral infections, gut microbiome alterations)

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This can be a network of interconnected evidence, previously envisaged in the implementation of the cytoprotection effects, consistent beneficial particular evidence that BPC 157 therapy counteracts dopamine, serotonin, glutamate, GABA, adrenalin/noradrenalin, acetylcholine, and NO-system disturbances