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This underdiagnosis can lead, besides death in 20% when it is not appropriately treated, to Korsakoffs syndrome, a severe dysfunction often following untreated Wernickes encephalopathy, that does not remit even with thiamine treatment and is associated with chronic alcohol abuse and chronic thiamine deficiency (40, 42)

Rhonda Patrick: I think the take home there is a lot of people with a darker skin living in sub-Saharan Africa or people living in India with darker skin or in the Philippines, these equatorial regions where there's, you tend to see darker skin because it's protection from the burning rays of the sun

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It is highly individualized by your healthcare provider based on factors like your age, weight, treatment goals, and baseline pituitary function

~ Int J Mol Sci