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doi: 10.1096/fasebj.31.1_supplement.993.3

Upon activation, Receptor Activator of Nuclear Factor-B Ligand (RANKL), is produced by CD4 + T cells, which attaches to the RANK receptor and triggers the NF-B and MAPK signaling pathways

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This antioxidative effect plays a critical role in protecting testicular cells from oxidative injury, especially in chemically-induced or disease-related testicular dysfunction