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In this study, there was no correlation between 3-THP levels and depressive symptoms

This phenomenon indicates that the diuretic and natriuretic effects of DPP-4i are mediated by preventing the degradation of GLP-1

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A 15-year follow-up study published in 2011 found that patients with a rapidly aging cardiovascular system who received epithalamin treatment for 2-3 years experienced a 1.6-1.8 fold decreased mortality rate compared with the control group [12]