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Tryptophan metabolism, from nutrition to potential therapeutic applications

GLP stands for glucagon like peptide and the receptors for GLP-1 are expressed mainly in pancreatic beta-cells, where its activation can lead to multiple acute and long term effects

Brefeldin A (BFA), a ER-to-Golgi transport inhibitor, and monensin, a Golgi-to-PM transport inhibitor, abrogated VRK2 overexpression induced increase in the expression of SLC7A11 at PM level (Fig

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So that was how we actually started looking at a hypothesis for Alzheimer's and Parkinsons