tirzepatide vs metformin Should be stopped in a patient with an HbA1c of 6.7% who recently started tirzepatide? Mounjaro vs Metformin for Diabetes

According to the Summary of Product Characteristics (SmPCs), GLP-1 medications commonly cause nausea (reported in approximately 20-40% of patients with semaglutide and 12-21% with dulaglutide), vomiting, and diarrhoea, particularly during initial treatment and dose escalation

Matrix metalloproteinases (MMP) manipulate extracellular matrix remodeling and PASMCs proliferation [35,36,37]

Kalec et al

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