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In the case of MET-097i, it is a GLP-1 RA analog that has an extended half-life of ~15-16 days, which is many fold that of native GLP-1 peptide and more than 2x the half-life of semaglutide (GLP-1 RA)

Nausea, constipation, and appetite loss are expected and manageable

Prescribing of the compounds must be based upon the professional judgment of the licensed health care provider after considering the patients unique medical condition and factors including body weight, size and overall health status

"Maintaining a strong core is important for all of us, and good pelvic floor strength goes hand-in-hand with body weight exercises or classes such as barre my personal favorite or Pilates," said Dr

Secher A, Jelsing J, Baquero AF, Hecksher-Sorensen J, Cowley MA, Dalboge LS, et al