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Individuals with severe GI conditions Gastroparesis, severe inflammatory bowel disease, and other conditions affecting GI motility could be worsened by a compound that further slows gastric emptying

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Vitamin D supplementation upregulates and induces innate anti-microbial and antiviral defense mechanisms, including induction of the anti-microbial peptide cathelicidin and interleukin-17 and downregulation of the lymphocyte membrane receptors that promote virus infectivity thereby reducing the adverse clinical effects of infection [98]

Investigated for its role in satiety-related signaling pathways and glucose-associated biomarkers in controlled research models