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Effect of L-carnitine supplementation and aerobic training on FABPc content and b-HAD activity in human skeletal muscle
It is FDA-approved for short-term use only (up to 12 weeks) Many doctors limit prescriptions to 3 months at a time Some physicians may prescribe it for longer periods "off-label" if they believe the benefits outweigh the risks The short-term limitation comes from a lack of long-term clinical trials and historical concerns about stimulant effects on the heart
References Bulgari, R., Franzoni, G
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Koeth RA, Wang Z, Levison BS, Buffa JA, Sheehy BT, Britt EB, Fu X, Wu Y, Li L, Smith JD, DiDonato JA, Chen J, Li H, Wu GD, Lewis JD, Warrier M, Brown JM, Krauss RM, Tang WH, Bushman FD, Lusis AJ, Hazen SL: Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
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