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Notably, Nav1.6 channels mediate transient, persistent (I NaP ), and resurgent sodium (I NaR ) currents, making major contributions to firing frequency and membrane resonance properties, as demonstrated in knockout mouse studies (Enomoto et al., 2006

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In C57BL/6 mice, the absence of either protein leads to deficient type I IFN production and early mortality (138, 158, 159)

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(l-3-carboxy-2-hydroxypropyl)trimethylammonium Hydroxide, Inner Salt 35

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