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Response to treatment - If vitamin B12 supplements and dietary changes seem to resolve hair loss symptoms, it supports the diagnosis

B12 injections deliver methylcobalamin, the metabolically active form of vitamin B12, directly into muscle tissue

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Subcutaneous administration at 50mg produces approximately 4050% NNMT enzyme inhibition, while 100mg achieves 6075% inhibition

An underactive thyroid (hypothyroidism) often leads to constipation and bloating, while an overactive thyroid (hyperthyroidism) can cause frequent bowel movements