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doi: 10.1002/9780470999615.ch44

In the context of early brain injury following subarachnoid hemorrhage (SAH), topiramate significantly reduced the elevated levels of TNF-, IL-1, and IL-6 induced by SAH, suggesting that topiramate may exert neuroprotection via its anti-inflammatory effects (Tian et al., 2015)

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The process usually involves submitting more detailed medical records and a letter of medical necessity from your doctor