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Microglia expresses some pattern recognition receptors that are engaged by pathogen-associated molecular patterns, triggering microglia activation

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Studies in inflammatory bowel disease models show KPV reducing intestinal inflammation markers without the systemic immunosuppressive effects associated with conventional treatments

doi: 10.1186/s12951-023-01951-x

Therefore, in-depth anatomic and molecular knowledge of the ferroptosis involving in the pathogenesis of eye diseases can provide novel targets and ideas for medical healthcare, prevention, and treatment of the associated diseases