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Analytical Biochemistry, Introduction to in vivo Magnetic Resonance Spectroscopy (MRS): A method to non-invasively study metabolism

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In one example, GSH-driven nanoparticle disintegration releases indomethacin to inhibit PTGS2 while reducing Pt 4 + to cytotoxic Pt 2 + , thereby amplifying cisplatin-induced pyroptosis in pancreatic cancer 218

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Membranes were blocked with 5% BSA (##9048-46-8, Sigma-Aldrich, MO, USA) in Tris-buffered saline (##1610716, Bio-Rad, CA, USA) containing 0.05% Tween-20 (##9005-64-5, Sigma-Aldrich, MO, USA) (TBST) for 1 h at room temperature