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Whether this is due to cumulative immune modulation or other factors is unclear

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However, sometimes the opposite is true

Horn, DO, MPH, DABOM, MFOMA, medical director at the University of Texas Center for Obesity Medicine and Metabolic Performance and clinical assistant professor in the department of surgery at University of Texas McGovern Medical School in Houston, said the weight loss observed in ATTAIN-2 was lower than what was observed in ATTAIN-1, but added that adults with type 2 diabetes usually lose less weight with obesity pharmacotherapy than the nondiabetes population