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In an open-label phase II trial, curcumin treatment (8 g/day) in combination with the anticancer drug gemcitabine was associated with severe abdominal pain in 7 out of 17 patients with advanced pancreatic cancer, leading to the treatment being discontinued in five patients while curcumin dosage was reduced to 4 g/day in two patients (79)

Sean Wharton, an internal medicine specialist who treats patients with Type 2 diabetes and obesity in the Toronto area

Discontinuation Trends and Persistence Patterns Despite the clinical benefits of GLP-1 receptor agonists, discontinuation remains a challenge

Glutathione is also available as a 1000mg or 2000mg add-on

Peak plasma concentration occurs 13 days post-dose