Serum potassium levels should be monitored during the first 48 hours of treatment in patients with pernicious anemia
In ACLY -knockout cell lines, the addition of exogenous acetate at physiological blood concentrations sustained acetyl-CoA levels and lipogenic metabolites via ACSS2 induction, suggesting that circulating acetate is likely adequate for compensatory lipid synthesis 80,105
K.OsorioD.BatraS
5,6 In addition, receptor activator of nuclear factor kappa beta ligand (RANKL), that plays a crucial role in osteoclast activity and bone resorption, 21 also directly influences pancreatic beta-cell function and overall metabolism, with its activity being compromised in obesity and T2D
Laugeray A, Launay JM, Callebert J, Surget A, Belzung C, Barone PR