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Globally, direct and indirect costs linked to obesity and related sleep disorders reach into the hundreds of billions, reflecting the burden from cardiovascular disease, diabetes, and medical utilization

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If severe erythema, edema, vesicle formation (e.g., vesicular rash), or crusting develops, topical tretinoin should be discontinued until skin integrity is restored

Boys born to mothers who have asthma are more likely to develop n-6/n-3 PUFA than girls

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