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Additionally, using a humidifier in your bedroom at night can help prevent overnight mouth dryness, and avoiding caffeine, alcohol, and salty foodswhich worsen dehydrationsupports saliva production

However, the potential immunosuppressive effects of JAK inhibitors also pose challenges, particularly in immunocompromised individuals or those with concurrent infections

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In adipose (fat) tissue, GIP receptor activation appears to improve lipid buffering capacity and insulin sensitivity, which helps mitigate some of the gastrointestinal side effects typically caused by pure GLP-1 stimulation