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Evidence for the traditional inflammatory theory is as follows: tumor necrosis factor alpha (TNF-), IL-6, IL-1, IL-17, and other inflammatory cytokines involved in RA could exert pro-osteoclastogenic effects and suppress bone formation in the appropriate environment via adequate signals, such as the receptor activator of nuclear factor kappa-B ligand (RANKL) and macrophage colony-stimulating factor (M-CSF)

Nutritional bars fortified with DPP-IV inhibitory collagen peptides offer sustained energy while helping to regulate blood glucose levels, making them a valuable option for individuals with diabetes [176]

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