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Older people and those who are pregnant, or breastfeeding can also have low levels of the vitamin, as well as people who naturally struggle to absorb B-12 from their diet

Contrary to expectations, the tripeptide has extremely low bioavailability through injections

Journal of Clinical Pharmacology, 55(12), 1459-1465

[68] And some articles in the popular press, such as those criticizing the pharmaceutical industry for marketing drugs for off-label use (with concern of ethics violations) have made strong statements about whether doctors can prescribe HGH off-label: "Unlike other prescription drugs, HGH may be prescribed only for specific uses

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