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Neuroprotection and Mood Regulation Semax protects neurons from oxidative stress and inflammation, factors involved in stroke and neurodegenerative diseases

Overall, despite potential lean mass loss, all CVOTs using long-acting GLP-1RAs resulted in favorable CV outcomes, also independent of age (59)

In the SURMOUNT-1 trial, participants with obesity or overweight achieved average weight reductions of 15-22% of body weight after 72 weeks, depending on the dose

For cardiomyopathy, GLP-1RAs improve mitochondrial function via regulating autophagy and inflammatory signaling, as well as not only mediate the inhibition of myocardial apoptosis, but also improve cardiac energy metabolism

Xue et al., 2004b