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While its stable at room temperature for several weeks, long term storage requires -20C

The figure 25.3 % surpasses: Tirzepatide SURMOUNT-1: 22.5 % Semaglutide STEP-1: 14.9 % Retatrutide Phase 2: 24.2 % (comparable, but Phase 3 results for Retatrutide are still lacking) It raises the question whether CagriSema will be the first molecule with an effect truly comparable to bariatric surgery (typically 2530 % reduction)

GLP-1 receptor activation slows gastric emptying (making food stay in the stomach longer, which extends satiety), reduces glucagon secretion (lowering blood sugar), and acts on hypothalamic neurons to reduce hunger drive

Wherever you choose to inject Wegovy, divide the section up into smaller sections and choose a different area to inject each week

Finally, translational studies should focus on establishing robust in vitroin vivo correlations that link regional deposition to brain exposure and pharmacodynamic outcomes, enabling rational dose selection and improved predictability across patient populations