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Therefore, hypercortisolemia may also contribute to the severe bone loss incurred and the highly prevalent psychiatric comorbidities in women with anorexia nervosa . Hypothalamic amenorrhea is another characteristic feature of AN, and has been attributed to a state of severe energy deficit from restricted energy intake, increased energy expenditure or both

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however, during oxidative stress, Nrf2 dissociates from Keap1 and translocates to the nucleus where it binds to antioxidant response elements

Janet will also address how RDNs are seizing new opportunities in business and communications