is glp 1 an incretin hormones and the satiation signal Incretin axis and incretin-based therapies:

CJC-1295/Ipamorelin is combination peptide therapy that consists of two powerful compounds, CJC-1295 (growth hormone releasing hormone analog) and Ipamorelin (growth hormone releasing peptide)

Food Rev Intl 36(2):193214

The mammalian enzyme is not well studied, but it is apparently composed of two identical subunits

Generally, more than 10,000 AP sites are produced daily in each cell, and can be efficiently repaired with the help of APE1 [6]

In pentobarbital anaesthetised rats, ipamorelin released GH with a potency and efficacy comparable to GHRP-6 (ED50 = 80+/-42nmol/kg and Emax = 1545+/-250ng GH/ml vs 115+/-36nmol/kg and 1167+/-120ng GH/ml)