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10.1038/s41418-020-00728-1 14 Che YaacobN
Methods: EphA2 expression and signaling was assessed in mice fed a high fat diet (HFD) for 8 and 24 weeks, in human liver samples from NASH patients, and in HuH7 cells treated with palmitic acid (FA), low density lipoprotein (LDL), and/or fructose
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The consequent derailment of the cellular behavior can thus lead towards apoptosis (a natural damage-limiting self-digestion of critically damaged cells, [85]), necrosis (an auto-sustaining, propagating tissue damage) and towards neoplastic transformation (an uncontrolled, invasive cellular growth)
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