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In the diabetes trials, meaningful weight effects plus A1C reductions may drive dual benefit appeal (i.e

These data were in line with the hypothesis that neuromuscular junctions, which are the synapses between MNs and muscle fiber, could represent the starting site of MN dysfunction in ALS [269]

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Early transcriptomic studies using cDNA microarrays, followed by bulk RNA sequencing (RNA-seq) provided foundational insights into transcriptional changes in aging MuSCs, highlighting disruptions in myogenic programs, mitochondrial function, and inflammatory regulation