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Ferroptosis promotes the development of AS through inflammation, endothelial cell dysfunction, and the formation of foam cells, using ferroptosis inhibitors in AS could reverse these effects, which may provide new targets and strategies for the prevention and treatment of AS

MASLD is the hepatic manifestation of metabolic syndrome (metS), driven by genetic variants like PNPLA3 rs738409 G and strongly associated with metabolic comorbidities, including obesity, T2DM, hyperlipidaemia and hypertension (810)

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