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Refrigeration at 2-8C slows these degradation pathways by reducing molecular kinetic energy, giving peptides dramatically extended shelf life compared to room temperature storage

J Child Adolesc Psychopharmacol 23:329336

Timing can vary depending on the severity of symptoms, the underlying cause, diet, medications, stress levels, and whether the gut issue is inflammatory, infectious, structural, or functional

It can also help preserve muscle mass during weight loss, crucial for maintaining metabolism and preventing muscle loss