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73 Halford, J

Alzheimer's & Dementia Journals+2The Lancet+2 A meta-analysis pooling many clinical trials (though mostly for diabetes endpoints) suggested that GLP-1 RAs (versus placebo or other drugs) may reduce risk of dementia among diabetics

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"The degree of mean weight reduction seen in SURMOUNT-2 has not been previously achieved in phase 3 trials for obesity or overweight and type 2 diabetes." Tirzepatide is a once-weekly GIP (glucose-dependent insulinotropic polypeptide) receptor and GLP-1 (glucagon-like peptide-1) receptor agonist