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The Effects of Tirzepatide on Kidney Disease As tirzepatide's role has been widely centered around decreasing the incidence of complications of diabetes mellitus, one must consider its impact on the development of diabetic nephropathy and chronic kidney disease (CKD)

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In agreement with serum cytokine levels, activation of their downstream signals including STAT1 and STAT3 in the liver was lower in ethanol-fed Aldh2 -/- mice than in ethanol-fed WT mice (figure 2B)

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