tirzepatide and semaglutide tablets vs. Semaglutide: Which is Best for Weight Loss? Semaglutide vs Tirzepatide, same medication

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Finally, hepatic impairment can affect gluconeogenesis and medication metabolism, though tirzepatide itself does not require dose adjustment in liver disease

Appetite 64 , 8188 (2013)

For reference, NICE guidance on currently licensed weight management medicines such as TA875 for semaglutide (Wegovy) requires a BMI threshold, evidence of weight-related health conditions, and engagement with a specialist weight management programme

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