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Mitomycin c induces apoptosis in rheumatoid arthritis fibroblast-like synoviocytes via a mitochondrial-mediated pathway

Biohacker Protocol (experimental) Dose: 0.5 1.0 mg (= 1020 clicks) Duration: 4 6 weeks Frequency: 1 2 per week Cycle Interval: 2 weeks off before repeating Goal / Description: Microdose approach to minimize nausea and flushing in tolerance studies

Post-transfusion recovery, metabolomics, and proteomics analyses were performed on these mice to validate findings from the J:DO cohort