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Large and complex studies are needed to identify and detail the changes at the mitochondrial level and the therapeutic approaches ( Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have demonstrated pleiotropic effects, including reducing mitochondrial ROS generation

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doi:10.3390/medicina59040778

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injections (between 15:00 and 17:00) of 100 nmol kg 1 MK-801, 10 nmol kg 1 semaglutide, 100 nmol kg 1 GLP-1MK-801 or vehicle, with concomitant measurements of body weight and food intake

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Finally, as discussed in section XIX.B.7

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