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Drugmakers, regulators, insurers, and healthcare providers are all preparing for the possibility that generic GLP-1 drugs could expand treatment access while also changing prescribing patterns and long-term care strategies

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GLP-1 medications work by: Slowing down the emptying of the stomach, which helps to reduce appetite and promote feelings of fullness

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Weight loss in particular, but also cardiorenal benefits and other potential advantages, have encouraged wider use, and several further GLP-1RAs with ever longer circulating half-lives are advancing in development, aiming to leverage the convenience of administration with minimal gastrointestinal side effects (Table 2) [37]